TORONTO, ON – SEPTEMBER 16: Actor Ryan Reynolds attends the “Mississippi Grind” premiere during the 2015 Toronto International Film Festival at Roy Thomson Hall on September 16, 2015 in Toronto, Canada. (Photo by Sonia Recchia/Getty Images)

What’s next for Ryan Reynolds after the record-setting Deadpool opening? Reynolds is in talks to star with Mission: Impossible – Rogue Nation‘sRebecca Ferguson in Life, a Skydance Productions film that Daniel Espinosa will direct from a script by Reynolds’ Deadpool scribes Paul Wernick and Rhett Reese. Espinosa and Reynolds teamed previously on Safe House.

Espinosa signed on last November, and talks with Reynolds were going on before the film surpassed the wildest dreams of anyone by grossing $150 million domestic and $282 million global in its opening five-day weekend. Skydance’s David Ellison and Dana Goldberg are producing with Bonnie Curtis and Julie Lynn. Paramount’s expected to be the distributor. It’s a big-scale film focusing on a Mars mission that finds intelligent alien life.